Title: La Sota Vaccination Does Not Offer Satisfactory Protection Against Velogenic Newcastle Disease Virus Infection In Chickens- A Review
La Sota vaccination is the major vaccine used in the control of Newcastle disease (ND) of chickens in most countries of Europe and United States of America where millions of chickens are kept in one farm at a time. La Sota vaccine is administered through drinking water and can be easily administered on millions of chickens in few hours. Furthermore, the predominant field ND virus pathotype in these countries is the mesogenic virus for which La Sota vaccination is effective in providing protection. But this same vaccine has been found to be ineffective against velogenic ND virus pathotype which is enzootic in Africa, Middle and Far East. This makes large scale poultry production difficult in these areas. The Komarov ND vaccine which is effective against the velogenic ND virus is administered intramuscularly and requires individual handling of the chickens which is not possible where millions of chickens are housed together.